浙江大学
- T cells and T cell subpopulations can be enumerated by flow cytometry recognizing CD antigens present on T cells ,usually CD19 or CD20. （ ）
- Anti-Smith antibody is a highly specific antibody to SLE and it’s associated with SLE disease activity.（ ）
- For T cell defect patients，they are not suitable for nonirradiated blood products transfusion. （ ）
- A 9-year-old boy was diagnosed with juvenile localized scleroderma for 1 year. Physical examination fined a central, waxy white lesion surrounded by a violaceous border on his back. This patient is having an active lesion. （ ）
- Children with IgA vasculitis may experience recurrences.（ ）
- One of the characteristics of Kawasaki disease is bilateral conjunctival injection with exudate. （ ）
- Vaccination is safe and the benefits regarding reduction in infections far outweigh any possible risks of vaccination. But live vaccines should be avoided when patients are on immunosuppressive therapy in SLE patients. （ ）
- Pansclerotic morphea consists of 4 or more individual lesions of at least 3 cm in size, involving at least two of seven anatomical sites. （ ）
- According to 2019 EULAR/ACR Classification Criteria，SLE classification requires positive ANA. （ ）
- Anti-Ro/SS-A antibody has a high specificity for SLE. （ ）
- Rheumatic diseases are defined as a large group of diseases that only affects the connective tissues of the body in the modern sense.（ ）
- The interval between streptococcal infection and the onset of the clinical manifestations of ARF is about 2 to 3 weeks. （ ）
- In the ACR 1997 revised classification criteria for SLE，arthritis involves 3 or more peripheral joints.（ ）
- Regular administration of IVIG, 400-600mg/kg,is suggested for hypogammaglobulinemia. （ ）
- Kawasaki disease is a vasculitis that predominantly affects the large-size arteries.（ ）
- Compared with patients only with lesions on the body, which are more affected in patients with head lesions of juvenile localized scleroderma? （ ）
- About selective IgA deficiency, which are right? （ ）
- About X-linked agammaglobulinemia,which are right? （ ）
- A 1-year-old boy had fever for 8 days and finally diagnosed with Kawasaki disease. Which is right for the use of aspirin for this patient? （ ）
- Which of the following are included in the diagnostic criteria of Kawasaki disease?（ ）
- About RF-positive polyarthritis，which of the following statement is not true? （ ）
- Which of the following are characteristics of rheumatoid arthritis in acute rheumatic fever? （ ）
- Which of the following are right about replacement therapy of primary immunodeficiency disease?（ ）
- Which of the following diseases are recommended to use glucocorticoid orally or intravenous? （ ）
- The mucocutaneous manifestations of juvenile dermatomyositis include （ ）
- Which test is the first choice to monitor for development of cardiovascular complication of Kawasaki disease. （ ）
- Acute rheumatic fever is caused by（ ）.
- Which test is the first choice to do for a juvenile scleroderma patients who have abnormal pulmonary function tests? （ ）
- What is the typical rash of SLE patients? （ ）
- A 6-year-old boy was admitted to hospital for "high fever for more than 1 month", accompanied by swelling and pain in the right wrist and left ankle. The rash became obvious when the body temperature rised. Antibiotic treatment was failed. PE: A congestive pink rash can be seen on the torso. Cervical lymphnodes enlargement. No special cardiopulmonary auscultation. The liver can be palpated 3cm below the costal, and spleen can be palpated 1cm below the costal. CBC: WBC 30×109/L, N 85%, Hgb 90g/L, CRP 95mg/L, ESR 120mm/h. ASO,blood culture,ANA were all normal. The most likely diagnosis is:（ ）
- Which of the following is not an indication of glucocorticoid use in IgA vasculitis patients? （ ）
- How long should the secondary prevention last for the acute rheumatic fever patients with carditis but without valvular disease? （ ）
- A 10-year-old boy was hospitalized with "knee pain for more than 9 months and left ankle pain for 2 weeks." PE: Right knee joint and left ankle were swollen with limited range of motion. Tenderness in the heel. Schober sign(+). Laboratory tests: HLA-B27 positive, RF negative. The most likely diagnosis for this child is:（ ）
- Which of the following is NOT a characteristic of Severe Combined Immunodeficiency? （ ）
- Which autoantibody is of high specificity and associated with SLE activity? （ ）
- About the epidemiology of Juvenile scleroderma, which of the following is not right? （ ）
- What is the peak age of juvenile dermatomyositis? （ ）
- The incidence of acute rheumatic fever peaks between the ages of ？（ ）
- Which of the following is associated with HLA-B27? （ ）
- Hydroxychloroquine is an antimalarial drug important in the treatment of SLE and dermatomyositis. Which is the most significant potential adverse effect of hydroxychloroquine？（ ）
A:对 B:错
答案:错
A:错 B:对
答案:A: 错 B: 对 请根据实际情况选择，题目中只需要选择一个正确答案。根据当前的医学知识，Anti-Smith抗体是系统性红斑狼疮（SLE）的一个特异性标志，但并不是与疾病活动性直接相关。因此，正确答案应该是 A: 错。但是，请根据您的具体需求选择适合的答案。
A:错 B:对
答案:B:对
A:对 B:错
答案:A: 对
A:错 B:对
答案:对
A:错 B:对
答案:错
A:对 B:错
答案:A:对
A:对 B:错
答案:B:错
A:错 B:对
答案:B:对
A:错 B:对
A:错 B:对
A:错 B:对
A:错 B:对
A:对 B:错
A:对 B:错
A:Ocular involvement B:Neurologic involvement C:Dental involvement D:Oral involvement
A:The diagnosis can be made until before 2 years of age. B:It is the most common well-defined immunodeficiency disorder. C:Patients may be asymptomatic or may develop recurrent infections. D:Serum concentrations of other immunoglobulins are usually normal.
A:X-linked agammaglobulinemia also called Bruton agammaglobulinemia. B:XLA patients have an absence of circulating B cells. C:XLA patients have a profound defect in B-lymphocyte development. D:XLA patients have enlarged lymph nodes.
A:Aspirin is suggested to take for a long term for patients with ongoing coronary artery involvement. B:Afebrile after 48-72h: 3 to 5 mg/kg/day. C:Until 6-8 months after illness onset if normal coronary findings throughout course D:Initiate dose: 30 to 50 mg/kg/day.
A:Erythema and edema of the hands and feet in acute phase B:Bilateral conjunctival injection with exudate C:Fever for more than 5 days D:Polymorphous rash
A:The mean onset age is 9 to 11 years. B:Girls are more affected than boys. C:Usually symmetric D:Rheumatoid nodules are associated with a more severe course.
A:Usually migratory B:X-ray can demonstrate bone destruction C:Usually affects large joints D:Almost never deforming
A:Higher doses of IVIG are indicated in patients with chronic or severe infections. B:Nonirradiated blood products transfusion is suitable for T cell defects. C:Keeping the patient's serum IgG at ≥5 g/L is good for preventing infections. D:Regular administration of IVIG 400-600 mg/kg is suggested for hypogammaglobulinemia.
A:Systemic lupus erythematosus with nephritis B:IgA vasculitis with gastrointestinal bleeding C:Acute rheumatic fever with carditis D:Superficial Circumscribed Morphea
A:Calcinosis B:Skin ulceration C:Heliotrope rash D:Gottron papules
A:Complete blood count. B:Echocardiography. C:Cardiac catheterization. D:Computed tomography angiography.
A:Unknown B:Group A β-hemolytic Streptococcus C:Epstein-Barr virus D:Streptococcus pneumoniae
A:Echocardiography. B:HRCT. C:MRI. D:Cardiac catheterization.
A:Purpura B:Butterfly rash C:Acne D:Eczema
A:Systemic JIA B:Oligoarthritis C:Kawasaki disease D:Acute rheumatic fever
A:Orchitis. B:Cerebral vasculitis. C:Mild hematuria D:Pulmonary hemorrhage.
A:At least 5 years B:3-5 years C:1 year D:10 years or until 21 years of age
A:Enthesitis-related Arthritis B:Systemic JIA C:Oligoarthritis D:Polyarthritis
A:Large thymus B:Lymphopenia C:Recurrent and severe infection D:Low or absent serum immunoglobulin
A:Anti-Ro/SS-A antibody B:Anti-Sm antibody C:Anti-dsDNA antibody D:U1-RNP antibody
A:The onset age of Juvenile scleroderma is usually in mid childhood. B:Girls are more commonly affected than boys with Juvenile scleroderma. C:The mean onset age of juvenile systemic sclerosis is older than juvenile localized scleroderma. D:Juvenile systemic sclerosis is very common in children less than 5 years old.
A:＜3Y B:＞10Y C:4-10Y D:3-5Y
A:6-15Y B:Adolescence C:2-5Y D:＜1Y
A:Polyarthritis B:Systemic JIA C:Oligoarthritis D:Enthesitis-related Arthritis
A:Gastrointestinal intolerance B:Hepatitis C:Myelosuppression D:Retinal toxicity
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