第四章单元测试
- Which of the following DNA damages belongs to exogenous DNA damage ( ).
- Which type of DNA point mutations will not lead to the change in amino acid ( ).
- which base substitution below belongs to “Transition” point mutation.( )
- Which is wrong below as described for directly undoing DNA damages repair.( )
- In which process GG-NER and TC-NER show different( )
- The deficiency of NER repair proteins is susceptible to_ disease.( )
- During mismatch repair in prokaryotes, the newly synthesized DNA is recognized by the lack of ( ) modification( )
- During double stranded DNA break repair, NHEJ shows more precise compared to HR. ( )
- DNA damage is the main cause for the increased frequency of gene mutation. ( )
- Base excision repair is one of DNA repair pathways to corrects large base lesions .( )
A:Instability of DNA structure B:Inaccuracy in DNA replication C:Endogenous Oxidative DNA damage D:Ionizing radiation
答案:Ionizing radiation
A:Missense mutation B:Nonsense mutation C:None of them D:Silent mutation
A:C→T B:A→C C:A→T D:G→T
A:There is no any DNA synthesis B:Pyrimidine dimer caused by UV can be repaired by directly undoing DNA damage repair process in human cells. C:O6-methylguanine methyltransferase can directly remove O6 alkylations on guanine residues by directly undoing DNA damage repair. D:Converting altered nucleotide back to original form.
A:DNA strand unwinding B:Nucleotides resynthesis C:DNA Strand excision D:DNA lesion recognition
A:Sickle HbC B:Lynch syndrome C:Chronic myelogenous leukemia D:Xeroderma pigmentosum
A:Deamination B:Methylation C:Acetylation D:Phosphorylation
A:错 B:对
A:错 B:对
A:错 B:对
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