第十四章测试
1.The main limitation to the rational design of new drug entities is ( ).
A:lack of detailed chemical and physical understanding of complex biological systems in healthy and diseased states B:unexpected action C:general cytotoxity D:awesome complexity of biological macromolecules
答案:A
2.Today’s useful drugs arise from ( )
A:chemical synthesis B:natural products C:combinations of both sources D:only natural products 3.What’s the reason for the search for new drugs gradually took on a more rational basis? ( )
A:biologists learned more about the biological mechanisms in health and disease B:the abilities of chemists to synthesize, isolate, and characterize new compounds grew C:biologists learned more about the action of drugs D:Failure of former methods 4.Who plays a vital role in understanding the underlying biological mechanisms? ( )
A:Nutritionists B:Pharmacologists C:Microbiologists D:Endocrinologists E:Biochemists and physiologists 5.Organic chemists and biochemists derive natural products from ( ).
A:animal B:marine organisms C:microbial D:plant 6. Morphine, quinine, digitalis, ergot and atropine were derived from plant sources, and their therapeutic uses were based on ancient serendipitous discoveries.( )
A:对 B:错 7. As the abilities of chemists to synthesize, isolate, and characterize new compounds grew and as biologists learned more about the action of drugs and about biological mechanisms in health and disease, the search for new drugs gradually took on a more rational basis.( )
A:错 B:对 8. In the past three decades the biological sciences have undergone a major redirection toward molecular understanding of biological systems.( )
A:错 B:对 9. Because of the awesome complexity of biological macromolecules, progress in quantitative understanding of physical or electronic interactions of drugs with key biological systems has been slow and tortuous.( )
A:错 B:对 10. Organic chemists in the pharmaceutical industry synthesize hundreds of new compounds every day.( )
A:对 B:错

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